1-Methoxy-3,4-dinitrobenzene → N-Cyclopropyl-4-(6-methoxy-1H-benzo[d]imidazol-2-yl)benzamide

HRID 2284272Notes

Reaction equation

HRID 2284272 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[C:5]([N+:12]([O-])=O)[CH:4]=1.[CH:15]1([NH:18][C:19]([C:21]2[CH:28]=[CH:27][C:24]([CH:25]=O)=[CH:23][CH:22]=2)=[O:20])[CH2:17][CH2:16]1>>[CH:15]1([NH:18][C:19](=[O:20])[C:21]2[CH:28]=[CH:27][C:24]([C:25]3[NH:12][C:5]4[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[CH:7][C:6]=4[N:9]=3)=[CH:23][CH:22]=2)[CH2:16][CH2:17]1

Participants

3

Reactant 2

HCID 128605041-Methoxy-3,4-dinitrobenzeneHCID 28818865N-cyclopropyl-4-formylbenzamide

Product 1

HCID 69674898N-Cyclopropyl-4-(6-methoxy-1H-benzo[d]imidazol-2-yl)benzamide

Procedure

Compound 635 was prepared according to the procedure similar to that described in Scheme III from 1-methoxy-3,4-dinitrobenzene and 4-cyclopropylaminocarbonylbenzaldehyde. [M+H]+ calcd for C18H17N3O2: 308.14; found: 308.16.

Sources & evidence

ORD record
ord-e800cae2cf98403a8cad77268fe20b9d
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

Loading…