1-(3-Methyl-1,2,4-oxadiazol-5-yl)methoxy-3,4-dinitrobenzene → 4-(6-((3-Methyl-1,2,4-oxadiazol-5-yl)methoxy)-1H-benzo[d]imidazol-2-yl)-N-(1H-indol-6-yl)benzamide

HRID 2284284Notes

Reaction equation

HRID 2284284 reaction equation
[CH3:1][C:2]1[N:6]=[C:5]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-])=O)=[C:11]([N+:18]([O-])=O)[CH:10]=2)[O:4][N:3]=1.[NH:21]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([NH:30][C:31]([C:33]3[CH:40]=[CH:39][C:36]([CH:37]=O)=[CH:35][CH:34]=3)=[O:32])[CH:28]=2)[CH:23]=[CH:22]1>>[CH3:1][C:2]1[N:6]=[C:5]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]3[N:15]=[C:37]([C:36]4[CH:35]=[CH:34][C:33]([C:31]([NH:30][C:27]5[CH:28]=[C:29]6[C:24]([CH:23]=[CH:22][NH:21]6)=[CH:25][CH:26]=5)=[O:32])=[CH:40][CH:39]=4)[NH:18][C:11]=3[CH:10]=2)[O:4][N:3]=1

Participants

3

Reactant 2

HCID 866740061-(3-Methyl-1,2,4-oxadiazol-5-yl)methoxy-3,4-dinitrobenzeneHCID 866740144-(6-Indolylaminocarbonyl)benzaldehyde

Product 1

HCID 676873054-(6-((3-Methyl-1,2,4-oxadiazol-5-yl)methoxy)-1H-benzo[d]imidazol-2-yl)-N-(1H-indol-6-yl)benzamide

Procedure

Compound 660 was prepared according to the procedure similar to that described in Scheme III from 1-(3-methyl-1,2,4-oxadiazol-5-yl)methoxy-3,4-dinitrobenzene and 4-(6-indolylaminocarbonyl)benzaldehyde. [M+H]+ calcd for C26H20N6O3: 465.16; found: 465.04.

Sources & evidence

ORD record
ord-3e5c34be74df4e24a8f4a0101600729c
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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