2-Methoxyethoxy-3,4-dinitrobenzene → 4-(6-(2-Methoxyethoxy)-1H-benzo[d]imidazol-2-yl)-N-(1H-indol-5-yl)benzamide

HRID 2284285Notes

Reaction equation

HRID 2284285 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[C:8]([N+:15]([O-])=O)[CH:7]=1.[NH:18]1[C:26]2[C:21](=[CH:22][C:23]([NH:27][C:28]([C:30]3[CH:37]=[CH:36][C:33]([CH:34]=O)=[CH:32][CH:31]=3)=[O:29])=[CH:24][CH:25]=2)[CH:20]=[CH:19]1>>[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]2[N:12]=[C:34]([C:33]3[CH:32]=[CH:31][C:30]([C:28]([NH:27][C:23]4[CH:22]=[C:21]5[C:26](=[CH:25][CH:24]=4)[NH:18][CH:19]=[CH:20]5)=[O:29])=[CH:37][CH:36]=3)[NH:15][C:8]=2[CH:7]=1

Participants

3

Reactant 2

HCID 866740102-Methoxyethoxy-3,4-dinitrobenzeneHCID 866740164-(5-Indolylaminocarbonyl)benzaldehyde

Product 1

HCID 676882524-(6-(2-Methoxyethoxy)-1H-benzo[d]imidazol-2-yl)-N-(1H-indol-5-yl)benzamide

Procedure

Compound 661 was prepared according to the procedure similar to that described in Scheme III from 1-(2-methoxyethoxy-3,4-dinitrobenzene and 4-(5-indolylaminocarbonyl)benzaldehyde. [M+H]+ calcd for C25H22N4O3: 427.17; found: 426.99.

Sources & evidence

ORD record
ord-7ae34d6530b94ad8abf0c150ea16e14e
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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