2-Methoxyethoxy-3,4-dinitrobenzene → 4-(6-(2-Methoxyethoxy)-1H-benzo[d]imidazol-2-yl)-N-(2-methyl-1H-indol-5-yl)benzamide

HRID 2284286Notes

Reaction equation

HRID 2284286 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[C:8]([N+:15]([O-])=O)[CH:7]=1.[CH3:18][C:19]1[NH:20][C:21]2[C:26]([CH:27]=1)=[CH:25][C:24]([NH:28][C:29]([C:31]1[CH:38]=[CH:37][C:34]([CH:35]=O)=[CH:33][CH:32]=1)=[O:30])=[CH:23][CH:22]=2>>[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]2[N:12]=[C:35]([C:34]3[CH:33]=[CH:32][C:31]([C:29]([NH:28][C:24]4[CH:25]=[C:26]5[C:21](=[CH:22][CH:23]=4)[NH:20][C:19]([CH3:18])=[CH:27]5)=[O:30])=[CH:38][CH:37]=3)[NH:15][C:8]=2[CH:7]=1

Participants

3

Reactant 2

HCID 866740102-Methoxyethoxy-3,4-dinitrobenzeneHCID 866740174-(2-Methyl-5-indolylaminocarbonyl)benzaldehyde

Product 1

HCID 676872044-(6-(2-Methoxyethoxy)-1H-benzo[d]imidazol-2-yl)-N-(2-methyl-1H-indol-5-yl)benzamide

Procedure

Compound 662 was prepared according to the procedure similar to that described in Scheme III from 1-(2-methoxyethoxy-3,4-dinitrobenzene and 4-(2-methyl-5-indolylaminocarbonyl)benzaldehyde. [M+H]+ calcd for C26H24N4O3: 441.18; found: 441.02.

Sources & evidence

ORD record
ord-a0c0db1996794344a5481749b6fe02d8
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

Loading…