2-Methoxyethoxy-3,4-dinitrobenzene → 4-(6-(2-Methoxyethoxy)-1H-benzo[d]imidazol-2-yl)-N-(1H-indol-2-yl)benzamide

HRID 2284287Notes

Reaction equation

HRID 2284287 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[C:8]([N+:15]([O-])=O)[CH:7]=1.[NH:18]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[C:19]1[NH:27][C:28]([C:30]1[CH:37]=[CH:36][C:33]([CH:34]=O)=[CH:32][CH:31]=1)=[O:29]>>[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]2[N:12]=[C:34]([C:33]3[CH:32]=[CH:31][C:30]([C:28]([NH:27][C:19]4[NH:18][C:26]5[C:21]([CH:20]=4)=[CH:22][CH:23]=[CH:24][CH:25]=5)=[O:29])=[CH:37][CH:36]=3)[NH:15][C:8]=2[CH:7]=1

Participants

3

Reactant 2

HCID 866740102-Methoxyethoxy-3,4-dinitrobenzeneHCID 866740184-(2-Indolylaminocarbonyl)benzaldehyde

Product 1

HCID 676873624-(6-(2-Methoxyethoxy)-1H-benzo[d]imidazol-2-yl)-N-(1H-indol-2-yl)benzamide

Procedure

Compound 663 was prepared according to the procedure similar to that described in Scheme III from 1-(2-methoxyethoxy-3,4-dinitrobenzene and 4-(2-indolylaminocarbonyl)benzaldehyde. [M+H]+ calcd for C25H22N4O3: 427.17; found: 426.99.

Sources & evidence

ORD record
ord-942e8487882c4ac5aea6e3700ac29f33
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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