N-cyclopropyl-4-formylbenzamide → 4-(6-((4-Cyanobenzyl)oxy)-1H-benzo[d]imidazol-2-yl)-N-cyclopropylbenzamide

HRID 2284290Notes

Reaction equation

HRID 2284290 reaction equation
[C:1]([C:3]1[CH:22]=[CH:21][C:6]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-])=O)=[C:11]([N+:18]([O-])=O)[CH:10]=2)=[CH:5][CH:4]=1)#[N:2].[CH:23]1([NH:26][C:27]([C:29]2[CH:36]=[CH:35][C:32]([CH:33]=O)=[CH:31][CH:30]=2)=[O:28])[CH2:25][CH2:24]1>>[C:1]([C:3]1[CH:22]=[CH:21][C:6]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]3[N:15]=[C:33]([C:32]4[CH:31]=[CH:30][C:29]([C:27]([NH:26][CH:23]5[CH2:25][CH2:24]5)=[O:28])=[CH:36][CH:35]=4)[NH:18][C:11]=3[CH:10]=2)=[CH:5][CH:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 28818865N-cyclopropyl-4-formylbenzamideHCID 866740111-(4-Cyanobenzyl)oxy-3,4-dinitrobenzene

Product 1

HCID 683758964-(6-((4-Cyanobenzyl)oxy)-1H-benzo[d]imidazol-2-yl)-N-cyclopropylbenzamide

Procedure

Compound 669 was prepared according to the procedure similar to that described in Scheme III from 1-(4-cyanobenzyl)oxy-3,4-dinitrobenzene and 4-(cyclopropylaminocarbonyl)benzaldehyde. [M+H]+ calcd for C25H20N4O2: 409.16; found: 409.04.

Sources & evidence

ORD record
ord-304c38d36db14f5192cd5319828ac3e1
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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