4,4'-Diaminodiphenylamine → N-(4-((4-Aminophenyl)amino)phenyl)-4-(4-hydroxypiperidin-1-yl)benzamide

HRID 2284301Notes

Reaction equation

HRID 2284301 reaction equation
[CH:1]1[C:6]([NH2:7])=[CH:5][CH:4]=[C:3]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([NH2:15])=[CH:11][CH:10]=2)[CH:2]=1.[OH:16][CH:17]1[CH2:22][CH2:21][N:20]([C:23]2[CH:31]=[CH:30][C:26]([C:27](O)=[O:28])=[CH:25][CH:24]=2)[CH2:19][CH2:18]1>>[NH2:15][C:12]1[CH:13]=[CH:14][C:9]([NH:8][C:3]2[CH:2]=[CH:1][C:6]([NH:7][C:27](=[O:28])[C:26]3[CH:25]=[CH:24][C:23]([N:20]4[CH2:21][CH2:22][CH:17]([OH:16])[CH2:18][CH2:19]4)=[CH:31][CH:30]=3)=[CH:5][CH:4]=2)=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 108414,4'-DiaminodiphenylamineHCID 186175914-(4-Hydroxy-1-piperidinyl)benzoic acid

Product 1

HCID 67112995N-(4-((4-Aminophenyl)amino)phenyl)-4-(4-hydroxypiperidin-1-yl)benzamide

Procedure

Compound 749 was prepared according to the procedure described in Scheme IV from 4,4′-diaminodiphenylamine and 4-(4-hydroxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C25H26N4O3: 403.21; found 403.04.

Sources & evidence

ORD record
ord-d4fdbb79d1b54bac8b47ca787922a134
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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