4-(4-Hydroxy-1-piperidinyl)benzoic acid → HCID 67113655, compound

HRID 2284306Notes

Reaction equation

HRID 2284306 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([NH2:15])=[CH:11][C:10]=2[C:16]#[N:17])=[CH:4][CH:3]=1.[OH:18][CH:19]1[CH2:24][CH2:23][N:22]([C:25]2[CH:33]=[CH:32][C:28]([C:29](O)=[O:30])=[CH:27][CH:26]=2)[CH2:21][CH2:20]1>>[C:16]([C:10]1[CH:11]=[C:12]([NH:15][C:29](=[O:30])[C:28]2[CH:32]=[CH:33][C:25]([N:22]3[CH2:23][CH2:24][CH:19]([OH:18])[CH2:20][CH2:21]3)=[CH:26][CH:27]=2)[CH:13]=[CH:14][C:9]=1[NH:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][C:29](=[O:30])[C:28]2[CH:27]=[CH:26][C:25]([N:22]3[CH2:23][CH2:24][CH:19]([OH:18])[CH2:20][CH2:21]3)=[CH:33][CH:32]=2)=[CH:3][CH:4]=1)#[N:17]

Participants

3

Reactant 2

HCID 186175914-(4-Hydroxy-1-piperidinyl)benzoic acidHCID 86674026HCID 86674026, compound

Product 1

HCID 67113655HCID 67113655, compound

Procedure

Compound 834 was prepared according to the procedure described in Scheme IV from N1-(4-aminophenyl)-2-cyanobenzene-1,4-diamine and 4-(4-hydroxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C37H38N6O4: 631.30; found: 631.11.

Sources & evidence

ORD record
ord-9871b20f33654aebb5d8e7a69e58e903
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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