Cyclopropylamine → HCID 67112311, compound

HRID 2284318Notes

Reaction equation

HRID 2284318 reaction equation
[CH:1]1([NH2:4])[CH2:3][CH2:2]1.[C:5]([C:8]1[CH:13]=[CH:12][C:11]([N:14]2[C:22]3[C:17](=[CH:18][C:19]([C:23]([OH:25])=O)=[CH:20][CH:21]=3)[CH:16]=[N:15]2)=[CH:10][CH:9]=1)([OH:7])=O.[OH:26][CH:27]1[CH2:32][CH2:31][N:30]([C:33]2[CH:39]=[CH:38][C:36]([NH2:37])=[CH:35][CH:34]=2)[CH2:29][CH2:28]1>>[CH:1]1([NH:4][C:23]([C:19]2[CH:18]=[C:17]3[C:22](=[CH:21][CH:20]=2)[N:14]([C:11]2[CH:10]=[CH:9][C:8]([C:5](=[O:7])[NH:37][C:36]4[CH:38]=[CH:39][C:33]([N:30]5[CH2:29][CH2:28][CH:27]([OH:26])[CH2:32][CH2:31]5)=[CH:34][CH:35]=4)=[CH:13][CH:12]=2)[N:15]=[CH:16]3)=[O:25])[CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 69828CyclopropylamineHCID 167921071-(4-Aminophenyl)piperidin-4-olHCID 67114479HCID 67114479, compound

Product 1

HCID 67112311HCID 67112311, compound

Procedure

Compound 950 was prepared according to the procedure described in Scheme IV from cyclopropylamine, 1-(4-carboxyphenyl)-1H-indazole-5-carboxylic acid, and 4-(4-hydroxypiperidin-1-yl)aniline. [M+H]+ calcd for C29H29N5O3: 496.23; found: 496.02.

Sources & evidence

ORD record
ord-d5e9ea6d71a7410f9267f49d806cffee
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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