Cyclopropylamine → HCID 67112794, compound

HRID 2284319Notes

Reaction equation

HRID 2284319 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=1)[CH:6]=[CH:5]2.[CH:20]1([NH2:23])[CH2:22][CH2:21]1.[CH2:24]([O:27][CH:28]1[CH2:33][CH2:32][N:31]([C:34]2[CH:42]=[CH:41][C:37]([C:38](O)=[O:39])=[CH:36][CH:35]=2)[CH2:30][CH2:29]1)[CH:25]=[CH2:26]>>[CH2:24]([O:27][CH:28]1[CH2:29][CH2:30][N:31]([C:34]2[CH:35]=[CH:36][C:37]([C:38]([NH:1][C:2]3[CH:3]=[C:4]4[C:8](=[CH:9][CH:10]=3)[N:7]([C:11]3[CH:19]=[CH:18][C:14]([C:15](=[O:16])[NH:23][CH:20]5[CH2:22][CH2:21]5)=[CH:13][CH:12]=3)[CH:6]=[CH:5]4)=[O:39])=[CH:41][CH:42]=2)[CH2:32][CH2:33]1)[CH:25]=[CH2:26]

Participants

4

Reactant 3

HCID 69828CyclopropylamineHCID 67112746HCID 67112746, compoundHCID 67112874HCID 67112874, compound

Product 1

HCID 67112794HCID 67112794, compound

Procedure

Compound 951 was prepared according to the procedure described in Scheme IV from 4-(5-amino-1H-indol-1-yl)benzoic acid, cyclopropaneamine, and 4-(4-allyloxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C33H34N4O3: 535.26; found 535.10.

Sources & evidence

ORD record
ord-9837620f6bb64f599cb55db483dce266
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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