Cyclopropylamine → HCID 67113391, compound

HRID 2284327Notes

Reaction equation

[OH:1][CH:2]1[CH2:7][CH2:6][N:5]([C:8]2[CH:49]=[CH:48][C:11]([C:12]([NH:14][C:15]3[CH:16]=[C:17]4[C:21](=[CH:22][CH:23]=3)[N:20]([C:24]3[CH:47]=[CH:46][C:27]([C:28]([NH:30][C:31]5[CH:32]=[C:33]6[C:37](=[CH:38][CH:39]=5)[N:36]([CH2:40][C:41]([O:43]CC)=O)[CH:35]=[CH:34]6)=[O:29])=[CH:26][CH:25]=3)[CH:19]=[CH:18]4)=[O:13])=[CH:10][CH:9]=2)[CH2:4][CH2:3]1.[CH:50]1([NH2:53])[CH2:52][CH2:51]1>>[CH:50]1([NH:53][C:41](=[O:43])[CH2:40][N:36]2[C:37]3[C:33](=[CH:32][C:31]([NH:30][C:28](=[O:29])[C:27]4[CH:26]=[CH:25][C:24]([N:20]5[C:21]6[C:17](=[CH:16][C:15]([NH:14][C:12](=[O:13])[C:11]7[CH:48]=[CH:49][C:8]([N:5]8[CH2:4][CH2:3][CH:2]([OH:1])[CH2:7][CH2:6]8)=[CH:9][CH:10]=7)=[CH:23][CH:22]=6)[CH:18]=[CH:19]5)=[CH:47][CH:46]=4)=[CH:39][CH:38]=3)[CH:34]=[CH:35]2)[CH2:52][CH2:51]1

Participants

Reactant 2

HCID 69828Cyclopropylamine

HCID 67113203HCID 67113203, compound

Product 1

HCID 67113391HCID 67113391, compound

Procedure

Compound 969 was prepared by treatment of Compound 962 with cyclopropylamine. [M+H]+ calcd for C40H38N6O4: 667.30; found 667.31.

Sources & evidence

ORD record: ord-2bbc37e2062848b688672f1d2a91d1c7
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09144557B2

Reaction notes

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