6-Aminoindole → HCID 67113107, compound

HRID 2284329Notes

Reaction equation

HRID 2284329 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=1)[CH:6]=[CH:5]2.[NH2:20][C:21]1[CH:29]=[C:28]2[C:24]([CH:25]=[CH:26][NH:27]2)=[CH:23][CH:22]=1.[O:30]1[CH2:35][CH2:34][N:33]([CH2:36][CH2:37][N:38]2[C:46]3[C:41](=[CH:42][C:43]([C:47]([OH:49])=O)=[CH:44][CH:45]=3)[CH:40]=[CH:39]2)[CH2:32][CH2:31]1>>[NH:27]1[C:28]2[C:24](=[CH:23][CH:22]=[C:21]([NH:20][C:15]([C:14]3[CH:18]=[CH:19][C:11]([N:7]4[C:8]5[C:4](=[CH:3][C:2]([NH:1][C:47]([C:43]6[CH:42]=[C:41]7[C:46](=[CH:45][CH:44]=6)[N:38]([CH2:37][CH2:36][N:33]6[CH2:32][CH2:31][O:30][CH2:35][CH2:34]6)[CH:39]=[CH:40]7)=[O:49])=[CH:10][CH:9]=5)[CH:5]=[CH:6]4)=[CH:12][CH:13]=3)=[O:16])[CH:29]=2)[CH:25]=[CH:26]1

Participants

4

Reactant 3

HCID 2560966-AminoindoleHCID 63749289HCID 63749289, compoundHCID 67112874HCID 67112874, compound

Product 1

HCID 67113107HCID 67113107, compound

Procedure

Compound 972 was prepared according to the procedure described in Scheme IV from 4-(5-amino-1H-indol-1-yl)benzoic acid, 6-aminoindole, and 1-(2-morpholinoethyl)-1H-indole-5-carboxylic acid. [M+H]+ calcd for C38H34N6O3: 623.27; found 623.15.

Sources & evidence

ORD record
ord-ddbb409a710c4d9e8357a5d6d2c64eb1
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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