4-(4-Hydroxy-1-piperidinyl)benzoic acid → HCID 67113330, compound

HRID 2284337Notes

Reaction equation

HRID 2284337 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=1)[N:6]=[CH:5]2.[OH:18][CH:19]1[CH2:24][CH2:23][N:22]([C:25]2[CH:33]=[CH:32][C:28]([C:29](O)=[O:30])=[CH:27][CH:26]=2)[CH2:21][CH2:20]1>>[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([NH:17][C:29](=[O:30])[C:28]3[CH:27]=[CH:26][C:25]([N:22]4[CH2:23][CH2:24][CH:19]([OH:18])[CH2:20][CH2:21]4)=[CH:33][CH:32]=3)=[CH:13][CH:12]=1)[N:6]=[CH:5]2

Participants

3

Reactant 2

HCID 186175914-(4-Hydroxy-1-piperidinyl)benzoic acidHCID 83414202HCID 83414202, compound

Product 1

HCID 67113330HCID 67113330, compound

Procedure

Compound 990 was prepared according to the procedure described in Scheme IV from 5-hydroxy-1-(4-aminophenyl)indazole and 4-(4-hydroxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C25H24N4O3: 429.18; found: 429.07.

Sources & evidence

ORD record
ord-a4a2c1dbe80f4991a86ec2c81ca62332
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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