4-(4-Hydroxy-1-piperidinyl)benzoic acid → HCID 67113419, compound

HRID 2284344Notes

Reaction equation

HRID 2284344 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:12]=[C:13]3[C:17](=[CH:18][CH:19]=1)[NH:16][CH:15]=[CH:14]3)[N:6]=[CH:5]2.[OH:20][CH:21]1[CH2:26][CH2:25][N:24]([C:27]2[CH:35]=[CH:34][C:30]([C:31](O)=[O:32])=[CH:29][CH:28]=2)[CH2:23][CH2:22]1>>[NH:16]1[C:17]2[C:13](=[CH:12][C:11]([N:7]3[C:8]4[C:4](=[CH:3][C:2]([NH:1][C:31](=[O:32])[C:30]5[CH:29]=[CH:28][C:27]([N:24]6[CH2:25][CH2:26][CH:21]([OH:20])[CH2:22][CH2:23]6)=[CH:35][CH:34]=5)=[CH:10][CH:9]=4)[CH:5]=[N:6]3)=[CH:19][CH:18]=2)[CH:14]=[CH:15]1

Participants

3

Reactant 2

HCID 186175914-(4-Hydroxy-1-piperidinyl)benzoic acidHCID 86674031HCID 86674031, compound

Product 1

HCID 67113419HCID 67113419, compound

Procedure

Compound 1043 was prepared according to the procedure described in Scheme IV from 5-amino-1-(indol-5-yl)indazole and 4-(4-hydroxypiperidin-1-yl)benzoic acid.

Sources & evidence

ORD record
ord-04070fde3d8f40ffb7650c9b83188814
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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