HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodo-2-methoxynicotinaldehyde → HCID 84651909, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodo-2-methoxynicotinaldehyde | HCID 10038381 | — |
| Reactant | HCID 117678403 | HCID 117678403 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 84651909 | HCID 84651909 | — |
Reaction Steps
4-Iodo-2-methoxypyridine-3-carbaldehyde was converted to 1-methoxy-2,7-naphthyridine using the methods described by A. Numata et al., Synthesis 1999, 306-311. Subsequent hydrogenation in acetic acid, under platinum(IV) oxide catalysis, afforded the requisite 8-methoxy-1,2,3,4-tetrahydro-2,7-naphthyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145427B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-25c83b826ba044e28c57cafe71afdcf7 |
| Source note | uspto-grants-2015_09 |