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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2284516Generated: October 28, 2026

Isopropylethanediol → HCID 66726512, compound

https://huagongshe.com/reaction/2284516

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylethanediolHCID 7996—
Reactant2,6-dichloropyridine-3,5-dicarbonitrileHCID 850221—
Reactant1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-olHCID 57968699—
ProductHCID 66726512HCID 66726512—

Reaction Steps

This compound was prepared from 2,6-dichloropyridine-3,5-dicarbonitrile (obtained from Aces Pharma), 2-isopropoxyethanol, and benzo[c][1,2]oxaborole-1,5(3H)-diol in a similar manner to that of D230. 1H-NMR (400 MHz, DMSO-d6) δ (ppm) 1.0 (d, J=4.5 Hz, 6H), 3.42-3.45 (m, 1H), 3.49-3.51 (m, 2H), 4.14-4.16 (m, 2H), 5.01 (s, 2H), 7.3 (d, J=6.3 Hz, 1H), 7.39 (s, 1H), 7.81 (d, J=6.6 Hz, 1H), 8.94 (s, 1H), 9.28 (s, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09145429B2
Source datasetuspto-grants-2015_09
ORD IDord-d00bb7681f804c89ac763b7ceb6da97b
Source noteuspto-grants-2015_09