HCID 90052079, compound → HCID 90052211, compound

Participants

Reaction Steps

To 10% palladium-carbon (100 mg), a solution of tert-butyl 3-((3-nitrophenyl)amino)piperidine-1-carboxylate (C21, 229 mg) in tetrahydrofuran (10 mL) and methanol (4 mL) was added at room temperature, and the mixture was stirred at room temperature for 1 hour under a hydrogen atmosphere. The insoluble matter was removed by filtration through Cerite, and then the solvent was evaporated under reduced pressure to obtain tert-butyl 3-((3-aminophenyl)amino)piperidine-1-carboxylate (C22, 211 mg).

Provenance & Evidence