HCID 90052093, compound → HCID 90052170, compound

Participants

Reaction Steps

To 10% palladium-carbon (30 mg), a solution of tert-butyl 4-((3-nitrophenyl)amino)azepane-1-carboxylate (C25, 78 mg) in tetrahydrofuran (2 mL) and methanol (2 mL) was added at room temperature, and the mixture was stirred at the same temperature for 1 hour under a hydrogen atmosphere. The insoluble matter was removed by filtration through Cerite, and then the solvent was evaporated under reduced pressure to obtain tert-butyl 4-((3-aminophenyl)amino)azepane-1-carboxylate (C26, 64 mg).

Provenance & Evidence