HCID 90051731, compound → HCID 90052107, compound

Participants

Reaction Steps

To 10% palladium-carbon (50 mg), a solution of tert-butyl (2-((3-((benzyloxycarbonyl)amino)propyl)amino)cyclohexyl)carbamate (C39, 137 mg) in methanol (5 mL) was added at room temperature, and the mixture was stirred at room temperature for 4 hours under a hydrogen atmosphere. The insoluble matter was removed by filtration through Cerite, and then the solvent was evaporated under reduced pressure to obtain tert-butyl (2-((3-aminopropyl)amino)cyclohexyl)carbamate (C40, 101 mg).

Provenance & Evidence