HCID 90051713, compound → HCID 90052172, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of (4-(benzyloxy)-2-(methylthio)pyrimidin-5-yl)methanol (S26, 818 mg) in toluene (30 mL), manganese dioxide (8.13 g) was added at room temperature, and the mixture was stirred at 50° C. for 1 hour. The reaction mixture was cooled to room temperature, and then the insoluble matter was removed by filtration through Cerite. The solvent was evaporated under reduced pressure to obtain oily 4-(benzyloxy)-2-(methylthio)pyrimidine-5-carbaldehyde (S20, 666 mg).

Provenance & Evidence