HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 20545486, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 22483-35-8 | HCID 5068960 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | HCID 20545486 | HCID 20545486 | 90% |
Reaction Steps
1-Nitro-4-(2-phenoxy-ethoxy)-benzene is reduced and the resulting amine is heated in acetic anhydride and glacial acetic acid and nitrated with 70% strength nitric acid. 1-Acetamido-2-nitro-4-(2-phenoxy-ethoxy)-benzene is obtained in 90% yield (melting point: 104° to 106° C.). The amide is hydrolysed with potassium hydroxide in ethanol and the desired nitroamine is obtained in 98% yield (melting point 121° to 123° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04323682 |
| Source dataset | uspto-grants-1982_04 |
| ORD ID | ord-3c7c7874bbe04cebb84c7bbbc5c1cdc8 |
| Source note | uspto-grants-1982_04 |