Butyl isocyanate → HCID 20523358, compound

Participants

Reaction Steps

Under nitrogen, a solution of 99.1 g of butyl isocyanate in 100 ml of methylene chloride is added dropwise in the course of 1 hour to a solution of 169.3 g of N-(β-cyanopropyl)-dimethylaminopropylamine in 500 ml of methylene chloride. The mixture is then refluxed for 2 hours, concentrated, and the residue is treated at 80° C. in a high vacuum in order to remove all low boiling constituents. Yield: 249.2 g (90.8%) of product in the form of an oil. Titration: 1 equivalent=261.9 g (theory 268.4 g).

Provenance & Evidence