Nicotinoyl chloride → HCID 20544047, compound

HRID 2285701Notes

Reaction equation

HRID 2285701 reaction equation
Cl.[CH2:2]([N:9]1[CH2:14][CH2:13][N:12]([C:15]2[NH:16][NH:17][C:18]3[CH:24]=[CH:23][CH:22]=[N:21][C:19]=3[N:20]=2)[CH2:11][CH2:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:25]([Cl:33])(=[O:32])[C:26]1[CH:31]=[CH:30][CH:29]=[N:28][CH:27]=1>>[ClH:33].[C:25]([N:17]1[C:18]2[CH:24]=[CH:23][CH:22]=[N:21][C:19]=2[N:20]=[C:15]([N:12]2[CH2:11][CH2:10][N:9]([CH2:2][C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=3)[CH2:14][CH2:13]2)[NH:16]1)(=[O:32])[C:26]1[CH:31]=[CH:30][CH:29]=[N:28][CH:27]=1

Participants

3

Reactant 2

HCID 82604Nicotinoyl chlorideHCID 20544049HCID 20544049, compound

Product 1

HCID 20544047HCID 20544047, compoundYield 83%

Procedure

3-(N-Benzylpiperazino)-1,2-dihydro-pyrido[2,3-e]-as-triazine hydrochloride is reacted with nicotinoyl chloride as described in Example 6. The title compound, melting at 218°-219° C., is obtained with a yield of 83%.

Sources & evidence

ORD record
ord-5574f4c8af464efaa7b9957d7b36afd5
Source dataset
uspto-grants-1982_04
Patent number
US04324786

Reaction notes

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