HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → N-Hexadecyl-3-pyridinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Hexadecylamine | HCID 8926 | — |
| Reactant | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-Hexadecyl-3-pyridinecarboxamide | HCID 459514 | 82.4% |
Reaction Steps
30.7 g of cetylamine and 33.2 g of pyridine were dispersed in 200 ml of acetonitrile, and 25 g of nicotinic acid chloride hydrochloride was added thereto under cooling with water. After reacting for 3 hours at 55° C., 800 ml of water was added thereto. The thus formed crystals were collected by filtration. Recrystallization from 500 ml of ethanol yielded 36.3 g of the end product. m.p. 85°-87° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04324855 |
| Source dataset | uspto-grants-1982_04 |
| ORD ID | ord-25c9654cff3a4d99b38997d25be60e4f |
| Source note | uspto-grants-1982_04 |