Morpholine → HCID 13146129, compound

HRID 2285787Notes

Reaction equation

Br[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH2:12])[N:3]=1.[NH:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1>>[N:13]1([C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH:5]=[C:4]([NH2:12])[N:3]=2)[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1

Participants

Reactant 2

HCID 8083Morpholine

HCID 2898451-Bromoisoquinolin-3-amine

Product 1

HCID 13146129HCID 13146129, compoundYield 92%

Procedure

1-Bromo-3-aminoisoquinoline is reacted with an equimolar quantity of morpholine as described in Example 1 to give 1-morpholinyl-3-aminoisoquinoline.

Sources & evidence

ORD record: ord-3cb832a7c1ac4e29a6ad43b92256b497
Source dataset: uspto-grants-1982_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04324894

Reaction notes

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