Ninhydrin → HCID 12803412, compound

Participants

Reaction Steps

A mixture of 3-azido-4-C-carboxy-2,3,4,6-tetradeoxy-D-arabino-hexose trimethylene dithioacetal (920 mg, 3.01 mmol) and 5% palladium-on-charcoal (375 mg) in methanol (25 ml) is hydrogenated at a pressure of 1 atmosphere for 5 hours at room temperature. The catalyst is then removed by filtration through Celite and the filtrate evaporated and dried in vacuo to give TLC-chromatographically-homogeneous, ninhydrin-positive amino acid trimethylene dithioacetal; yield 816 mg (97%).

Provenance & Evidence