HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentamethylsilylamine → 1-(3-(2-(Dimethylamino)ethenyl)-2,2-dimethylcyclopropyl)-2-propanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentamethylsilylamine | HCID 74965 | — |
| Reactant | Cyclopropaneacetaldehyde, 2,2-dimethyl-3-(2-oxopropyl)- | HCID 10888310 | — |
| Product | 1-(3-(2-(Dimethylamino)ethenyl)-2,2-dimethylcyclopropyl)-2-propanone | HCID 54524032 | 86.1% |
Reaction Steps
To 6.7 g of 2,2-dimethyl-3-(2-oxopropyl)cyclopropylacetaldehyde at 0° C. was added 5.2 g of trimethylsilyldimethylamine over a 5 min period. The resulting product was distilled through a spiral bantamware column to yield 6.7 g of the desired product having a boiling point of 85°-90° at 1 mm Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04324915 |
| Source dataset | uspto-grants-1982_04 |
| ORD ID | ord-34334f1ee39646e8942a2880e9290d6e |
| Source note | uspto-grants-1982_04 |