反应详情

A stirred mixture of 4 g. of 2-chloronicotinonitrile in 200 ml. of a saturated ethanolic ethylamine solution was heated under reflux for 5 hours. The solution was cooled and was diluted with 400 ml. of water. The precipitate of 2-ethylaminonicotinonitrile which formed was collected, air dried and was used directly in the next step without further purification.

1. additionA stirred mixture of 4 g
2. temperatureunder reflux for 5 hours
3. temperatureThe solution was cooled
4. additionwas diluted with 400 ml