Dimethylformamide → HCID 13059344, compound

Participants

Reaction Steps

Stir a mixture of 290 mg (0.82 mmol) of the bromo-ketoester of Example 5, 91 mg (1.4 mmol) of NaN3, and 4 ml of dry DMF at 25° C. for 1 hour. Dilute the mixture with ether, wash several times with water and then brine, dry over MgSO4, and remove the solvent in vacuo to give 210 mg of the desired azide (VII, R=CF3, R1,R2 =H, R3 =C6H5CH2) as an oil.

Provenance & Evidence