Acetic Acid → 3-Bromo-1,1-diphenylacetone

Participants

Reaction Steps

A solution of 2.1 g. of 1,1-diphenyl-2-propanone in 25 ml. of acetic acid is heated to 60°-70° C. and 0.5 ml. of bromine in 4 ml. of acetic acid is added dropwise. The reaction mixture is held at 60°-70° C. for one hour and then poured into ice. Toluene is added. The toluene layer is separated, washed with water, dried over magnesium sulfate and concentrated, giving 1-bromo-3,3-diphenyl-2-propanone.

Provenance & Evidence