Sodium Hydroxide → HCID 15571271, compound

Participants

Reaction Steps

A solution of 4.2 g. of 3-diphenylmethyl-2,3,5,6,7,8-hexahydrothiazolo[3,2-a][1,3]diazepin-3-ol hydrobromide in 50 ml. of 65% aqueous methanol is treated with 12 ml. of 1 N sodium hydroxide. The resulting solid is collected by filtration, washed with water and dried in vacuo at 40° C., giving the desired product, m.p. 123°--125° C.

Provenance & Evidence