HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Propyl-6-amino-5-nitrosouracil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-Amino-1-propyluracil | HCID 104562 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Propyl-6-amino-5-nitrosouracil | HCID 10703093 | — |
Reaction Steps
To 34.3 g (0.20 mol) of 6-amino-1-propyl-2,4-(1H,3H)-pyrimidinedione (II), dissolved in 900 ml hot water, was added 45 ml of 5 N HCl and 15 g of NaNO2 (0.22 mol) which was dissolved in water. After cooling the red crystals were filtered off and washed with water. Yield 33.3 g (83%) (III) NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04325956 |
| Source dataset | uspto-grants-1982_04 |
| ORD ID | ord-38d729baeddb4169b087b8f103280929 |
| Source note | uspto-grants-1982_04 |