HCID 20536592, compound → HCID 20542610, compound

Participants

Reaction Steps

A solution of 1-benzyl-4-(4-nitrophenoxy)-4-phenylpiperidine (1.95 g, 5 mM), in methanol (100 ml) was hydrogenated over 5% Pd/C at atmospheric pressure and room temperature. After the theoretical uptake of hydrogen had occurred (about 2 hours), the catalyst was removed by filtration and the solvents removed under reduced pressure. Recrystallisation of the residue from IPA (twice) gave the title compound (400 mg), m.p. 124°-6° C.

Provenance & Evidence