反应详情

A solution of 1-methyl-4-(2-nitrophenoxy)-4-phenylpiperidine (6.4 g) in methanol (200 ml) was hydrogenated at atmospheric pressure and ambient temperature until the theoretical uptake of hydrogen had occurred (about 2 hours). The catalyst was removed by filtration, the solvent removed under reduced pressure and the residue recrystallised twice from IPE to give the title compound (4.5 g) m.p. 129°-30°.

1. custom(about 2 hours)
2. customThe catalyst was removed by filtration
3. customthe solvent removed under reduced pressure
4. customthe residue recrystallised twice from IPE