Ethylene Oxide → HCID 20543108, compound

HRID 2286001Notes

Reaction equation

HRID 2286001 reaction equation
[CH3:1][C:2]1([CH2:14][CH3:15])[CH2:11][CH:10]([CH2:12][CH3:13])[CH:9]2[CH:4]([CH2:5][CH2:6][CH2:7][CH2:8]2)[NH:3]1.[CH2:16]1[O:18][CH2:17]1>C(O)CO>[OH:18][CH2:17][CH2:16][N:3]1[CH:4]2[CH:9]([CH2:8][CH2:7][CH2:6][CH2:5]2)[CH:10]([CH2:12][CH3:13])[CH2:11][C:2]1([CH3:1])[CH2:14][CH3:15]

Participants

4

Reactant 2

HCID 6354Ethylene OxideHCID 20543119HCID 20543119, compound

Product 1

HCID 20543108HCID 20543108, compound

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent

Procedure

Following the procedure given in E above, 75 grams of 2-methyl-2,4-diethyl decahydroquinoline were reacted with ethylene oxide in the presence of 50 milliliters of ethylene glycol at 200° C. for 10 hours to yield 1-(2'-hydroxyethyl)-2-methyl-2,4-diethyl decahydroquinoline, which had a boiling point of 140° C. at 0.8 mm Hg. The NMR and infrared spectra were consistent with the desired product. For formula of C16H31NO, the calculated carbon, hydrogen, nitrogen contents are 75.83% carbon, 12.33% hydrogen, and 5.53% nitrogen and the analyzed contents were 74.69% carbon, 12.24% hydrogen, and 5.14% nitrogen.

Sources & evidence

ORD record
ord-4ae67341508f43cd959b0d259a9cc67a
Source dataset
uspto-grants-1982_04
Patent number
US04326061

Reaction notes

Loading…