1-(2,6-Dimethylphenyl)-3-methylguanidine hydrochloride → HCID 178485094, compound

HRID 2286026Notes

Reaction equation

HRID 2286026 reaction equation
Cl.[CH3:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[NH:10][C:11]([NH:13][CH3:14])=[NH:12]>[OH-].[Na+]>[CH3:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([CH3:2])[C:4]=1[NH:10][C:11]([NH:13][CH3:14])=[NH:12]

Participants

3

Reactant 1

HCID 1784850951-(2,6-Dimethylphenyl)-3-methylguanidine hydrochloride

Product 1

HCID 178485094HCID 178485094, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

The free base is prepared by dissolving 1-(2,6-dimethylphenyl)-3-methylguanidine hydrochoride in 10% sodium hydroxide solution and extracting with ether. The ether is dried and evaporated to dryness to obtain 1-(2,6-dimethylphenyl)-3-methylguanidine.

Workup

  1. customThe free base is prepared
  2. extractionextracting with ether
  3. dry with materialThe ether is dried
  4. customevaporated to dryness

Sources & evidence

ORD record
ord-5a3be00c12ba4f7fa5f47144483fbb0e
Source dataset
uspto-grants-1982_04
Patent number
US04326074

Reaction notes

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