Methyl Isocyanate → HCID 86737664, compound

Participants

Reaction Steps

3-(N-chloroacetyl-2,6-dimethylphenylamino)-2-butanone oxime (2.6 g) was dissolved in 75 ml methylene chloride and 5 drops of triethylamine were added. To this mixture was added 2.6 g methylisocyanate and the solution was stirred at room temperature. The solution was refluxed for 5 minutes and solvent was stripped. The oil was crystallized in ethanol-water to yield 3 g tan product. This product is tabulated as Compound No. 17 in Table I.

Provenance & Evidence