Ethyl isobutyrate → 6-(7-Hydroxyheptyl)-7-(4-methyl-3-oxopent-1-enyl)-1,4-dioxaspiro [4,4]nonane

関与物質

反応手順

The dimethyl 3-methyl-2-oxobutylphosphonate (b.p. 125°-135° C./11 mm.Hg; νmax 2950 cm-1, 1710 cm-1, 1470 cm-1, 1260 cm-1, 820 cm-1), used as a starting material in the above preparation, was prepared by proceeding in a similar manner to that hereinbefore described in Example 9(iv) for the preparation of dimethyl 2-oxo-4-phenylbutylphosphonate, but substituting the appropriate quantity of ethyl isobutyrate for the ethyl β-phenylpropionate used as starting material.

情報源と証拠