Formaldehyde → HCID 12836711, compound

Participants

Reaction Steps

A mixture of 0.76 g 2-propargyl-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine, 15 ml 37% aqueous formalin and 7.5 ml dimethylformamide was heated under reflux for 1.5 hours. The solvent was removed under reduced pressure to obtain a white semi-solid. This semi-solid was purified by chromatography on silica gel using a chloroform/methyl alcohol (75:1) mixed solvent to obtain 0.61 g of a white semi-crystalline product.

Provenance & Evidence