HCID 14673956, compound → HCID 14674145, compound

Participants

Reaction Steps

A solution of 6-amino-3,4-dihydro-2,2-dimethyl-7-nitro-trans-4-piperidino-2H-benzo[b]pyran-3-ol (140 mg) in ethanol (30 ml) was hydrogenated over 5% palladium-charcoal (0.1 g) until uptake of hydrogen ceased. The solution was filtered (Kieselguhr) and evaporated to dryness in vacuo to give unstable 6,7-diamino-3,4-dihydro-2,2-dimethyl-trans-4-piperidino-2H-benzo[b]pyran-3-ol (0.12 g) which was used immediately in the following reactions. Rf (0.3) in ethyl acetate-hexane 1:2 (colourless spot) compared with starting material with Rf (0.6) as an orange spot.

Provenance & Evidence