HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 13060839, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Bromo(phenyl)acetic acid | HCID 97919 | — |
| Reactant | HCID 178525282 | HCID 178525282 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 13060839 | HCID 13060839 | 61% |
Reaction Steps
A mixture of 12.8 g. (0.04 m.) 4-(4-chlorophenyl)-2-mercapto-5-thiazole acetic acid of (B.) above and 8.8 g. (0.04 m.) α-bromophenylacetic acid in 200 ml. acetone and 40 ml. each of glacial acetic acid and acetic anhydride is heated in an open flask for 2 hours. The solvents are removed and the residual solid triturated with acetonitrile. 13.4 g. (61% yield) of title product is obtained, m.p. 175°-180° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04327221 |
| Source dataset | uspto-grants-1982_04 |
| ORD ID | ord-daab163b687141ae9f43812be4decb5a |
| Source note | uspto-grants-1982_04 |