Acetic Acid → HCID 131712701, compound

Participants

Reaction Steps

Crude 3-nitro-1-phenyl-1-(m-chlorophenyl)propan-2-ol (43 g; 0.15 M) in ethanol (600 ml) containing acetic acid (9.3 ml:l equiv.) and RaNi (approx. 20 g.,) was hydrogenated at 250 p.s.i. H2 pressure for 4 hours. The mixture was filtered and evaporated to give a greenish oil. Trituration with ether (250 ml) gave the required product (34 g; 72%) as an off-white solid M.pt. 132°-137° C.

Provenance & Evidence