Methoxydiphenylphosphine → HCID 21464710, compound

HRID 2286299Notes

Reaction equation

HRID 2286299 reaction equation
[CH3:1][C:2]1([C:8](Cl)=[O:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.C[O:12][P:13]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH3:1][C:2]1([C:8]([P:13](=[O:12])([C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 77636MethoxydiphenylphosphineHCID 41892451-Methylcyclohexanecarbonyl chloride

Product 1

HCID 21464710HCID 21464710, compound

Procedure

Using a method similar to that described for compound XI, 80 parts of 1-methyl-1-cyclohexanecarboxylic acid chloride and 108 parts of methoxydiphenylphosphine, in the absence of a solvent, give 100 parts of 1-methyl-cyclohexanoyldiphenylphosphine oxide as an oily crude product, which is purified by chromatography over silica gel (using toluene as the migrating agent).

Sources & evidence

ORD record
ord-d03c129da733409e94f8923f25ecd713
Source dataset
uspto-grants-1981_05
Patent number
US04265723

Reaction notes

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