2,6-Dimethoxybenzoyl chloride → (2,6-Dimethoxyphenyl)(diphenylphosphoryl)methanone

HRID 2286302Notes

Reaction equation

HRID 2286302 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH3:13])[C:4]=1[C:5](Cl)=[O:6].C[O:15][P:16]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C1(C)C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH3:13])[C:4]=1[C:5]([P:16](=[O:15])([C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:6]

Participants

4

Reactant 2

HCID 748102,6-Dimethoxybenzoyl chlorideHCID 77636Methoxydiphenylphosphine

Product 1

HCID 21982674(2,6-Dimethoxyphenyl)(diphenylphosphoryl)methanone

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

20 parts of 2,6-dimethoxybenzoyl chloride are suspended in 20 parts by volume of toluene in the same apparatus as described for the preparation of initiator XX, and 21.6 parts of methoxydiphenylphosphine are added dropwise to this mixture at 50°-55° C., whilst stirring. Stirring is continued for 3 hours at 50° C. and the product is then recrystallized directly from toluene. 32 parts of yellowish crystals are obtained. Melting point: 124°-126° C.

Workup

  1. additionare added dropwise to this mixture at 50°-55° C.
  2. stirringStirring
  3. customthe product is then recrystallized directly from toluene
  4. custom32 parts of yellowish crystals are obtained

Sources & evidence

ORD record
ord-2ee99ad7c3f64fbd83b293e8f908c11d
Source dataset
uspto-grants-1981_05
Patent number
US04265723

Reaction notes

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