Potassium Hydroxide → HCID 178474155, compound

HRID 2286315Notes

Reaction equation

HRID 2286315 reaction equation
F[S:2]([CH2:5][CH2:6][NH:7][C:8]1[CH:13]=[C:12]([NH:14][C:15](=[O:17])[CH3:16])[CH:11]=[CH:10][C:9]=1[CH3:18])(=[O:4])=[O:3].[OH-:19].[K+:20]>O>[K:20][CH:5]([S:2]([OH:19])(=[O:4])=[O:3])[CH2:6][NH:7][C:8]1[CH:13]=[C:12]([NH:14][C:15](=[O:17])[CH3:16])[CH:11]=[CH:10][C:9]=1[CH3:18]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 21161676HCID 21161676, compound

Product 1

HCID 178474155HCID 178474155, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

N-(2-Fluorosulfonylethyl-2-methyl-5-acetamidoaniline (13.7 g, 0.05 m) is stirred with water (100 ml.) and potassium hydroxide (5.0 g) at room temperature for 2 hrs. when thin-layer chromatography shows reaction to be complete. The aqueous solution is used in the coupling reaction without further isolation.

Workup

  1. customreaction
  2. customThe aqueous solution is used in the coupling reaction without further isolation

Sources & evidence

ORD record
ord-106e624eeb7e4129aab8900eb6d99f36
Source dataset
uspto-grants-1981_05
Patent number
US04265812

Reaction notes

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