Furan-2-thiol → HCID 23462909, compound

HRID 2286409Notes

Reaction equation

HRID 2286409 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[SH:6].[BrH:7].[CH3:8][N:9]1[CH2:15][CH2:14][C:13]2=[CH:16][C:17](=[O:21])[C:18](=[O:20])[CH:19]=[C:12]2[CH2:11][CH2:10]1>CO>[BrH:7].[OH:21][C:17]1[C:18]([OH:20])=[CH:19][C:12]2[CH2:11][CH2:10][N:9]([CH3:8])[CH2:15][CH2:14][C:13]=2[C:16]=1[S:6][C:2]1[O:1][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 83164Furan-2-thiolHCID 12668031HCID 12668031, compound

Product 1

HCID 23462909HCID 23462909, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1.1 g. (0.0011 mole) of 2-furanthiol in 200 ml. of methanol is added portionwise 2.3 g. (0.0084 mole) of 3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-dione hydrobromide. After stirring for 1 hour at room temperature the reaction mixture is filtered and the filtrate concentrated in vacuo to give 7,8-dihydroxy-6-(2-furylthio)-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide.

Workup

  1. filtrationis filtered
  2. concentrationthe filtrate concentrated in vacuo

Sources & evidence

ORD record
ord-4a361e65273741e4b7a0338a7807064d
Source dataset
uspto-grants-1981_05
Patent number
US04265890

Reaction notes

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