HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Anisidine → ethyl N-[2-cyano-3-(4-methoxyanilino)acryloyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | ethyl N-(2-cyano-3-ethoxyacryloyl)carbamate | HCID 230015 | — |
| Product | ethyl N-[2-cyano-3-(4-methoxyanilino)acryloyl]carbamate | HCID 3759870 | — |
Reaction Steps
Following the above procedure, p-methoxyaniline (0.05 mol) is reacted with α-cyano-β-ethoxy-N-ethoxycarbonylacrylamide (0.05 mol) to yield α-cyano-β-(4-methoxyanilino)-N-ethoxycarbonylacrylamide, which is cyclized by heating in tetralin to yield 5-cyano-1-(4-methoxyphenyl)uracil, m.p. 304.5°-306.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04266056 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-c8796885114e457ea1ef57011531ae93 |
| Source note | uspto-grants-1981_05 |