HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 13014427, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 2,6-Dichloroaniline | HCID 11846 | — |
| Reactant | ethyl N-(2-cyano-3-ethoxyacryloyl)carbamate | HCID 230015 | — |
| Reactant | HCID 70546525 | HCID 70546525 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetralin | HCID 8404 | — |
| Product | HCID 13014427 | HCID 13014427 | — |
Reaction Steps
2,6-Dichloroaniline and α-cyano-β-ethoxy-N-ethoxycarbonylacrylamide in ethanol is refluxed 3 days and hexane added to prepare α-cyano-β-(2,6-dichloroanilino)-N-ethoxycarbonylacrylamide, which is cyclized by heating in tetralin to yield 5-cyano-1-(2,6-dichlorophenyl)uracil, m.p. 273°-274.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04266056 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-2b70df1e0d3f4eadba4aa05a1d3f1e13 |
| Source note | uspto-grants-1981_05 |