HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 23461648, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Acetamido-5-chloro-2-methoxybenzoic acid | HCID 10988496 | — |
| Reactant | HCID 23461650 | HCID 23461650 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 23461648 | HCID 23461648 | 124.7% |
Reaction Steps
Reaction between 4-acetylamino-5-chloro-2-methoxy benzoic acid (3.2 g, 0.013 mole), triethylamine (1.3 g) and N-n-butyl-N'-amino piperazine (2.06 g) (prepared in similar manner to that described in Example 5) and hydrolysis as described in Example 1 gave 4-amino-5-chloro-2-methoxy-N-[4-n-butyl-1-piperazinyl]benzamide (2.80 g, 63%) as colourless microcrystals, m.p. 173.5°-174° C. (ex. EtOAc/light petrol 40°-60°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04267175 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-b9932f56388d405bbbb508021cf5b3dc |
| Source note | uspto-grants-1981_05 |