HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Acetylaminocaproic acid → 1-(6-Acetylaminohexanoyl)-2-cyanoaziridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Acetylaminocaproic acid | HCID 2005 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | Aziridine-2-carbonitrile | HCID 118115 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-(6-Acetylaminohexanoyl)-2-cyanoaziridine | HCID 23461431 | — |
Reaction Steps
3.46 g. 6-Acetylaminohexanoic acid, 1.36 g. 2-cyanoaziridine and 4.3 g. dicyclohexylcarbodiimide are reacted in the usual manner in 35 ml. tetrahydrofuran and the reaction mixture then worked up to give 1.1 g. 1-(6-acetylaminohexanoyl)-2-cyanoaziridine which, after recrystallization from ethyl acetate-ligroin, melts at 74°-77° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04267174 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-5ed2d50db136443eb96c05537d095a21 |
| Source note | uspto-grants-1981_05 |